Chihuahuas are as easy to domesticate as any other breed if you breed them frequently and on a regular schedule. Puppies need to go outside as soon as they wake up in the morning, after every meal, after sleeping, after playing and just before bed. Using a drawer to restrict them when you can’t control them will teach them that they can control their bladder and prevent accidents at home. If they are not packed in crates, plan to take them out every 1-2 hours and do not put them in crates for more than two to four hours at a time, except overnight.